Research progress on major pharmacological activities of S-allyl-L-cysteine
10.3760/cma.j.issn.1673-4181.2017.06.013
- VernacularTitle:S-烯丙基-L-半胱氨酸主要药理活性研究进展
- Author:
Ganen MU
1
;
Zewei ZHOU
Author Information
1. 中国医学科学院 北京协和医学院放射医学研究所
- Keywords:
S-allyl-L-cysteine;
Pharmacological activities;
Metabolism;
Excretion
- From:
International Journal of Biomedical Engineering
2017;40(6):465-470
- CountryChina
- Language:Chinese
-
Abstract:
Oxidation and inflammation are associated with the pathological processes of most human diseases, posing a serious threat to human health. In recent years, researchers have extracted monomeric compounds from natural products for the prevention and treatments of diseases related to oxidation and inflammation. That has become a major trend in the study of anti-oxidant and anti-inflammatory drugs. Garlic, a natural product, has pharmacological activities such as anti-tumor, anti-inflammatory and detoxification and so on. Therefore, it is important to study and extract the active ingredients in garlic. As an active ingredient extracted from garlic, S-allyl-L-cysteine (SAC) has been extensively studied in cell and animal models. The main pharmacological activities of SAC and the related receptors were reviewed, and its mechanism of action in vivo and the beneficial effects on the corresponding diseases were summarized to provide the necessary basis for further study.
