Research Progress of Angiogenesis in Atherosclerotic Plaque in Chinese Medicine and Western Medicine.

Author: Lan MA ¹ ; Jin DAI ¹ ; Jie CHEN ¹ ; Hong-Wen CAI ¹ ; Jia-Ying LI ¹ ; Xin-Yao LI ¹ ; Shen-Jie CHEN ¹ ; Wei MAO ^{2
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Author Information

1. The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China.
2. The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310053, China. maoweilw@
3. com.
Publication Type:Journal Article
Keywords: Chinese medicine; Western medicine; angiogenesis; atherosclerotic plaque
From: Chinese journal of integrative medicine 2018;24(12):950-955
CountryChina
Language:English
Abstract: Angiogenesis in atherosclerotic plaque plays a critical role in the mechanism of atherosclerotic physiopathology. Present consensus shows that angiogenesis in atherosclerotic plaque is mainly resulted in hypoxia, inflammation and some pro-angiogenic factors. The homeostasis in plaque, which is hypoxic and infiltrated by inflammatory cells, may lead to angiogenesis, increase the plaque instability and the incidence rate of vascular events. This article reviews the progression of pathogenetic mechanism, physiopathological significance, relevant detecting technique and corresponding therapeutic methods of Chinese and Western medicine of angiogenesis in atherosclerotic plaque, so as to provide more theoretical basis for atherosclerotic clinical treatment.