Preparation and quality standard of standard decoction of Phellodendri Chinensis Cortex pieces.
10.19540/j.cnki.cjcmm.20180105.012
- Author:
Shu-Hui WANG
1
;
Zhe DENG
1
;
Jun ZHANG
1
;
Meng-Jiao JIAO
1
;
Guo-Yuan ZHANG
1
;
Jia SHI
1
;
Jin-Tang CHENG
1
;
An LIU
1
Author Information
1. Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Phellodendri Chinensis Cortex pieces;
quality standard;
standard decoction
- From:
China Journal of Chinese Materia Medica
2018;43(5):873-878
- CountryChina
- Language:Chinese
-
Abstract:
To prepare standard decoction of Phellodendri Chinensis Cortex pieces, establish quality standards, and provide reference for evaluating the quality of formula granule of Phellodendri Chinensis Cortex. 15 batches Phellodendri Chinensis Cortex pieces in different levels of quality were collected from market. The standard extraction process was used to prepare the standard decoction, and then the transfer rate of the index components berberine and phellodendrine was calculated to measure dry extraction ratio and pH value. So the method for Phellodendri Chinensis Cortex's fingerprint and content determination of index components was established. The result revealed that the extraction ratio was from 12.81% to 19.41%, with an average value of 16.54%. The transfer rate of berberine was at the range of 36.4%-56.6%, with an average value of 48.9%. The transfer rate of Phellodendri Chinensis Cortex piece was at the range of 47.5%-83.3%, with an average value of 63.1%. The pH value was between 5.2 and 5.9. The Similarity Evaluation System for Chromatographic Fingerprint of traditional Chinese medicine TCM (2012A) was used to analyze and compare the fingerprint and the similarity between the fingerprint of formula granule of Phellodendri Chinensis Cortex and the reference fingerprint was over 0.9. The preparation method in this paper showed good precision, stability and repeatability in fingerprint analysis, suitable for quality evaluation of Phellodendri Chinensis Cortex pieces standard decoction.
