Current progress in neuroimaging research on treatment resistant depression.
10.7507/1001-5515.201705086
- Author:
Wei PENG
1
;
Zhiyun JIA
2
;
Qiyong GONG
3
Author Information
1. Huaxi Magnetic Resonance Research Center (HMRRC), Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P.R.China;Department of Radiology, People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R.China.
2. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.
3. Huaxi Magnetic Resonance Research Center (HMRRC), Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.
- Publication Type:Journal Article
- Keywords:
brain function;
brain metabolism;
brain structure;
fronto-limbic system;
treatment resistant depression
- From:
Journal of Biomedical Engineering
2018;35(5):794-798
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common psychiatric disorder, and approximately 30% patients with depression do not respond effectively to standard antidepressant medication; this condition is termed treatment resistant depression (TRD) and its neurobiological mechanism remains unclear. Neuroimaging techniques can non-invasively explore changes in brain structure, function and metabolism. These techniques have been applied in neurobiological research of TRD and revealed critical abnormalities in brain structure, function and metabolism in fronto-limbic system. In this paper, we reviewed the latest progress in neuroimaging researches on TRD, providing new insight and imaging evidence for further neurobiological studies of TRD.
