Noninfectious Severe Early Chamber Reaction after Penetrating Keratoplasty.
- Author:
Su Jin LIM
1
;
Su Young KIM
;
Man Soo KIM
Author Information
1. Department of Ophthalmology, Gangnam St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul Korea. mskim@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Chamber reaction;
Inflammation;
Penetrating keratoplasty
- MeSH:
Anterior Chamber;
Cornea;
Corneal Opacity;
Diagnosis;
Dilatation, Pathologic;
Edema;
Follow-Up Studies;
Humans;
Hypersensitivity;
Inflammation;
Keratoconus;
Keratomileusis, Laser In Situ;
Keratoplasty, Penetrating*;
Medical Records;
Retrospective Studies;
Transplants;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2007;48(3):343-347
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report 8 cases of Noninfectious early anterior chamber reaction after penetrating keratoplasty (PKP), and to review relevant literature. METHODS: Retrospectively, we reviewed medical records of 8 patients who had undergo PKP from March 2001 to May 2004, associated with early severe chamber reaction. RESULTS: Preoperative diagnosis are corneal opacity (4 cases), keratoconus (2 cases), corneal ectasia after LASIK (1 case) and graft failure (1 case). Although they didn't show severe chamber reaction at first day after surgery, the anterior chamber reaction with cornea edema and decreased visual acuity had increased with time. We didn't give the additional treatment except increasing the number of instillation of topical steroid. The inflammation was improved within a week and the complete resolution was achieved during the follow-up in all cases. In all cases posterior synechia and anterior subcapsular opacity were found. CONCLUSIONS: It seems reasonable to conclude that a single common etiologic factor could not responsible for this syndrome. Non-infectious inflammation developing upon PKP may be caused by a multifactorial process like increased IOP, toxic anterior segment syndrome form surgical trauma or hypersensitivity reaction et al and viscoelastics effect.
