PRODUCTION AND CHARACTERISTICS OF ANTIBIOTICS FROM ANTAGONISTIC STRAIN OF BACILLUS MUCILAGINOSUS
- VernacularTitle:胶胨状芽孢杆菌拮抗菌株活性物质形成条件及其性质初步研究
- Author:
Guangye LIU
;
Yang LIN
;
- Publication Type:Journal Article
- Keywords:
Bacillus mucilaginosus , Antibiotic metabolite, Fermentational conditions
- From:
Microbiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Ingredients of medium and fermentational conditions of antagonistic strain of B mucilaginosus were studied The optimal medium composed of 2% maltose and 0 1% (NH 4) 2SO 4。 The optimal temperature was from 32℃ to 37℃ under 150 r/min shake condition and neutral pH kept was necessary for growth and antibiotic activity The antibiotic metabolite isolated from the fermentation liquid showed strong activity in inhibiting the growth of G + bacteria such as B cereus, Staphylococcus aureus and G - bacteria as Escherichia coli The isolate was determined as peptide compound because it rapidly losed activity over 60℃ or treated with pancreatic protease and according to its biochemical reaction
