Studies on immunoregulating effect in single and compatibility with Radix Aconiti and Radix Stephaniae Tetrandrae
- VernacularTitle:川乌配伍防己对动物免疫功能的调节作用
- Author:
Shaohua ZHANG
;
Lin QIN
;
Ling XUE
;
Ping WANG
;
- Publication Type:Journal Article
- Keywords:
Radix Aconiti (RA);
Radix Stephaniae Tetrandrae (RST);
compatibility;
immunoregulation;
adjuvant arthritis
- From:
Chinese Traditional and Herbal Drugs
1994;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Object The immunoregulation function was studied in experimental animals to observe the effect of single and/or combined use with Radix Aconiti (RA) and Radix Stephaniae Tetrandrae (RST). Methods The response of delayed type hypersensitivity (DTH) in mice, the phagocytosis of abdominal macrophages (M?) in mice, and the production of special antibodies in mice were observed. Results The two Chinese materia medica (CMM) in combination use could induce the increasing of phagocytosic function of M? hypoimmunitic model mice, the inhibiting on the responses of DTH in the hyperimmunitic model mice and the non immunosuppressive treated mice. On the production of special antibodies in mice, the enhance effect was found in RA used in single, and the suppressive effect was found when using the combination of the two CMM. Conclusion In accordance with the mechanism of the disorder between the anti inflammation effect and the induce inflammation effect to arthritis in the immune system, these data indicate that the bidirectional effect of combination of the two CMM used on the immune responses, may be the involved mechanism on treating arthritis.
