Research on Protective Effect of Jiusuyu on Gastric Mucosa of Acute Alcoholism Mice
- VernacularTitle:酒速愈对急性酒精中毒小鼠胃黏膜的保护作用
- Author:
Muxiang YANG
;
Wentao YU
;
Huazhou XU
;
Jinkuan HU
;
Guoming LI
;
- Publication Type:Journal Article
- Keywords:
Jiusuyu;
acute alcoholism;
superoxide dismutase(SOD);
malondialdehyde(MDA);
nitrogen monoxide(NO);
endothelins-1(ET-1)
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the protective effect and its mechanisms of Jiusuyu on gastric mucosa of acute alcoholism mice.Methods: Acute alcoholism mouse models were set up by intragastric administration of 56? Hongxing Erguotou wine,compared with Gehuajiecheng liquid,the effect of Jiusuyu on gastric mucosa pathological histology,SOD、MDA、NO and ET-1 of acute alcoholism mice were observed.Results: The gastric mucosa of mice in model group appeared obvious bleeding,fester and ulcer;a lot of phlegmonosis cells infiltrating could be seen below mucosa.At the same time the activity of SOD and level of NO in gastric mucosa were decreased(P
