Randomized,Open-label and active controlled study of PEG-IFN?-2a in the treatment of chronic hepatitis C in China
- VernacularTitle:聚乙二醇干扰素?-2a与干扰素?-2a治疗慢性丙型肝炎疗效、安全性的评估
- Author:
Daozhen XU
;
Yao XIE
;
Zhimeng LU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Polyethylene Glycols;
Hepatitis C like viruses;
Hepatitis C, chronic;
Interfron Alfa 2a
- From:
Chinese Journal of Infectious Diseases
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy, tolerability and safety profiles of PEG IFN alpha 2a(PEG IFN? 2a) in the treatment of chronic hepatitis C in China. Methods 208 patients with chronic hepatitis C were included, and divided into two groups randomly, PEG IFN? 2a group and IFN? 2a Group respectively. There was no significant difference between two groups in pretreatment HCV RNA, HCV genotype and other clinical data. The main parameters to valuate the efficacy were virological response and biochemical response. The side effects were intensively observed. Results Sustained virological response rate in PEG IFN? 2a group was significantly higher than that in IFN? 2a group (41.51% and 16.67% respectively, P
