THE INFLUENCE OF POLYSACCHARIDE OF SPIRULINA PLATENSIS ON INHIBITION ACTIVITY OF IMMOBILIZED PHYCOCYANIN AGAINST CANCER CELLS GROWTH
- VernacularTitle:藻多糖对固定化藻蓝蛋白抑癌作用的影响
- Author:
Yanqing GUAN
;
Baojiang GUO
;
- Publication Type:Journal Article
- Keywords:
polysaccharide of Spirulina platensis;
immobilized phycocyanin;
pancreatic cancer cells SW1990
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the influence of polysaccharide of Spirulina platensis(PSP) on inhibition activity of immobilized phycocyanin (PC) against proliferation of pancreatic cancer cells SW1990. Methods: PSP was added to the wells of cell culture polystyrene which was immobilized with PC, and SW1990 cells were cultured on this kind of biomaterial in serum free medium. Results: When the concentration of PSP was 15 mg/L, the inhibition activity was mainly caused by PSP, and when the concentrations were 10, 17.5 and 25 mg/L, PSP was cooperative with immobilized PC. The best immobilized amount of PC was 0.02 mg/well, which could inhibit 86% SW1990 cells. Conclusion: PSP can enhance the inhibition activity against pancreatic cancer cells SW1990 from immobilized PC.
