The effects of anti-depression therapy on post-stroke depression and neurologic rehabilitation in the elderly patients
- VernacularTitle:抗抑郁治疗对老年脑卒中后抑郁及康复的影响
- Author:
Xiaodong WANG
;
Zhaoan TAN
;
Zushun WU
;
Junfeng GAO
;
Meijiang FENG
;
- Publication Type:Journal Article
- Keywords:
Cerebrovascular accident;
Depression;
Fluoxetine;
Amitriptyline;
Rehabilitation
- From:
Chinese Journal of Geriatrics
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of anti depression therapy on post stroke and neurological rehabilitation in the elderly. Methods There were 178 post stroke depression (PSD) cases. They were divided into 3 groups: 64 cases taking Prozac once every morning about 20 80 mg daily; 58 cases taking amitriptyline twice everyday about 50 100 mg daily and 56 cases taking placebo as control group. All of them were on the regular treatment of cerebrovascular disease. All the cases were evaluated according to the HAMD score, neurological function impairment and ADL before treatment and 1 st , 2 nd , 4 th , 8 th week and 3 rd , 6 th , 12 th month after the treatment. Results At the 2 nd week, HAMD score dropped obviously from 27 7?6 9 to 17 3?5 9 in Prozac group, from 26 9? 6 9 to 15 7?4 2 in amitriptyline group, with significant difference vs pre treatment and the control groups ( P
