Paclitaxel and platinum-containing chemotherapy in 16 cases with advanced epithelial ovarian cancer
- VernacularTitle:紫杉醇联合铂类药物治疗16例晚期卵巢上皮癌
- Author:
Congzhu LI
;
Ping HUANG
;
Yuxia ZHAI
;
Al ET
- Publication Type:Journal Article
- Keywords:
ovarian neoplasms;
paclitaxel;
cisplatin;
carboplatin
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the therapeutic effect of paclitaxel and platinum containing chemotherapy (cisplatin or carboplatin) in women with epithelial ovarian cancer.Methods:We assigned 16 cases with advanced epithelial ovarian cancer after initial surgery to receive paclitaxel and cisplatin or carboplatin. Pcalitaxel (135 mg/m 2,over a period of 10 hours ) was administered iv once every 3 to 4 weeks, 24 control cases were treated with "CAP" or "CVP" regimen. Results:The overall median survival was significantly longer in the paclitaxel platinum group than in the cisplatin cyclophosphamide group (median, 35 vs. 22.5 months, P
