Study on the serum SOD,MDA and their relationship with T cell subsets in patients with hemorrhagec fever with syndrome
- VernacularTitle:肾综合征出血热患者血清超氧化物歧化酶、丙二醛含量和T淋巴细胞亚群的关系
- Author:
Yongri TAI
;
Weizhe CUI
;
Xueji HAN
;
Al ET
- Publication Type:Journal Article
- Keywords:
Hemorrhagic fever with syndrome(HFRS) Oxygen free radicals(OFR) Superoxidedismu tase(SOD) Malendiadeghyde(MDA) T cell subsets
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between the effects of oxygen free radicals (OFR) with T cell subsets on pathogenesis of hemorrhagic fever with syndrome(HFRS).Methods:Serum levels of SOD and MDA.T cell subsets in 54 patients with HFRS were sequentially investigate and correlation. Results:The level of serum SOD in febrile phase was lower than that of normal control.The level of serum MDA in febrile phase was higher than that of normal group;the sum of CD4 + cell in febrile phase was signficantly lower than that normal group,CD8 + cell was significantly higher than that of control group,and its changes must severe in oliguric phase.The resuts also showed that there was sum correlation existed between MDA and T cell subsets.Conclusion:These findings demonstrated that irregulating immunity of HFRS patients was correlation with OFR.
