A comparison of oxycodone and fentanyl in intravenous patient-controlled analgesia after laparoscopic hysterectomy.
10.4097/kjae.2015.68.3.261
- Author:
Nan Seol KIM
1
;
Kyu Sik KANG
;
Sie Hyeon YOO
;
Jin Hun CHUNG
;
Ji Won CHUNG
;
Yonghan SEO
;
Ho Soon CHUNG
;
Hye Rim JEON
;
Hyung Youn GONG
;
Hyun Young LEE
;
Seong Taek MUN
Author Information
1. Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea. ksjsk@schca.ac.kr
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Fentanyl;
Oxycodone;
Postoperative pain
- MeSH:
Analgesia, Patient-Controlled*;
Anesthesia;
Fentanyl*;
Humans;
Hysterectomy*;
Incidence;
Ketorolac;
Nausea;
Oxycodone*;
Pain, Postoperative;
Patient Satisfaction;
Postoperative Period
- From:Korean Journal of Anesthesiology
2015;68(3):261-266
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We planned to compare the effect of intravenous oxycodone and fentanyl on post-operative pain after laparoscopic hysterectomy. METHODS: We examined 60 patients were randomized to postoperative pain treatment with either oxycodone (n = 30, Group O) or fentanyl (n = 30, Group F). The patients received 10 mg oxycodone/100 microg fentanyl with ketorolac 30 mg before the end of anesthesia and then continued with patient-controlled analgesia for 48 h postoperatively. RESULTS: The accumulated oxycodone consumption was less than fentanyl during 8, 24 and 48 h postoperatively. Numeric rating score of Group O showed significantly lower than that of Group F during 30 min, 2, 4, 8 and 24 h postoperatively. The incidences of adverse reactions were similar in the two groups, though the incidence of nausea was higher in the Group O during the 24 and 48 h postoperative period. CONCLUSIONS: Oxycodone IV-PCA was more advantageous than fentanyl IV-PCA for laparoscopic hysterectomy in view of accumulated oxycodone consumption, pain control and cost beneficial effect. However, patient satisfaction was not good in the group O compared to group F.
