Optimization of the Formula of Compound Ginkgo Leaves Tablets by Orthogonal Experiment
- VernacularTitle:正交试验优选复方银杏叶片的处方研究
- Author:
Hualing WEI
;
Hongping PAN
;
- Publication Type:Journal Article
- Keywords:
Orthogonal design;
Compound ginkgo leaves tablets;
Formula
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the formula of the compound ginkgo leaves tablets.METHODS:The formula(dosage of low-substituted hydroxypropyl cellulose;the ratio between crude drug and loading agent and the dosage of micro-crystalline cellulose)was optimized using orthogonal design and multi-index(tablet weight variation and disintegration de-gree)comprehensive score method.RESULTS:The optimized formula was the following:the dosage of low-substituted hy-droxypropyl cellulose was5%;the ratio between crude drug and loading agent was1∶1and the dosage of microcrystalline cellulose was10%.CONCLUSION:The tablets are reasonable in formula and the forming quality of which is also good.
