Effects of FK506 and portal decompression on the outcome of porcine extended hepatectomy
- VernacularTitle:门静脉减压术和FK506对扩大肝切除术影响的实验研究
- Author:
Guangwen ZHOU
;
Chenghong PENG
;
Mingjun ZHANG
;
Weiyao CAI
;
Weiping YANG
;
Tanglei SHAO
;
Hongwei LI
- Publication Type:Journal Article
- Keywords:
Hepatectomy;
Portal pressure;
Tacrolimus
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo elucidate the effect of portal decompression and FK506 (FK) pretreatment on porcine extended hepatectomy.MethodsForty pigs were equally devided into 4 groups. Group A underwent 80% hepatectomy and portacaval shunt with FK pretreatment, group B did 80% hepatectomy and portacaval shunt, group C did 80% hepatectomy and FK pretreatment and group D did 80% hepatectomy. ResultsThe 5 day survival rate in Group A and B was 80% and 60% respectively, higher than 30% in Group C and 20% in group D ( P 200 mm H 2 O ( P
