Isolation and characterization of xanthine oxidase inhibitory constituents of Pyrenacantha staudtii
- Author:
Abiodun FALODUN
;
Muhammad Irfan QADIR
;
Muhanmad Iqbal CHOULDARY
- Publication Type:Journal Article
- Keywords:
flavonoid glycoside;
phenyl methanone;
xanthine oxidase;
Pyrenacantha staudtii;
IcacinaceaeCLC number:R284.1 Document code:A Article
- From:
Acta Pharmaceutica Sinica
2009;44(4):390-394
- CountryChina
- Language:Chinese
-
Abstract:
Six compounds have been isolated from the leaves of Pyrenacantha staudtii,two of which are new compounds.The new compounds have been characterized as kaempherol 3-O-β-rhamnopyranosyl (1→6)β-D-glucopyranoside (1) and 4-β-glucopyranosyl-(2-furyl)-5-methy-1,2-glucopyranoside phenylmethanone (2).The known compounds are 3-pyridinecarboxylic acid (3),β-sitosterol (4),sitosterol 3-O-β-glucopyranoside (5) and taraxerol (6).Their structures were determined by spectroscopic and chemical evidences.The two new compounds together with 3-pyridinecarboxylic acid showed significant in vitro xanthine oxidase inhibitory activity.To the best of our knowledge,this is the first report of these compounds from this plant.
