An experiment on ectopia osteogenesis of rhBMP-2/nHA/Co compound membrane
- VernacularTitle:rhBMP-2/nHA/Co复合膜异位成骨的实验研究
- Author:
Li ZHANG
;
Ning MA
;
Yanhai CHE
- Publication Type:Journal Article
- Keywords:
TypeⅠcollagen;
rhBMP-2;
Ectopia osteogenesis
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the ectopia osteogenesis ability of rhBMP-2/nHA/Co compound membrane.Methods:Two membranes were fabricated:(1) nHA/Co group(2) rhBMP-2/nHA/Co group.Both of them was evaluated after implantation under thigh muscle of nude mice for 10,20,30 days.Results:More bone-like structures in rhBMP-2/nHA/Co group were found,than that in nHA/Co group.Conclusion:Collagen and nano-HA are suitable sustained release systems for rhBMP-2 in animal experiment and the rhBMP-2/nHA/Co compound membrane can effectively induce ectopia osteogenesis.
