Durability of in vitro antimicrobial effect of polymethylmethacrylate denture base containing silver-supported antimicrobial agent of nanometer level
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:纳米载银树脂基托体外抗菌效果的持久性
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Riyue YU
			        		
			        		;
		        		
		        		
		        		
			        		Yongsheng ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Hailan FENG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Silver ion;
			        		
			        		
			        		
				        		Antimicrobial agent;
			        		
			        		
			        		
				        		Polymethylmethacrylate;
			        		
			        		
			        		
				        		Denture base;
			        		
			        		
			        		
				        		Durability of antimicrobial effect
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Practical Stomatology
	            		
	            		 2000;0(06):-
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective: To study the durability of the antimicrobial effect of polymethylmethacrylate (PMMA) denture base containing silver-supported antimicrobial agents of nanometer level against Streptococcus mutans and Candida albicans in vitro. Methods:The antimicrobial PMMA resin bases with the antimicrobial agent STR-1 at concentration of 5 mg/ml were prepared. Then the samples were divided into 4 groups: positive control group, the group immersed in distilled water at 57 ℃ for 14 days, the group irradiated by ultraviolet for 8 hours, and the group irradiated by ultraviolet for 8 hours after immersed in distilled water at 57 ℃ for 14 days. Then the inhibition ratios of the 4 groups against Streptococcus mutans and Candida albicans in vitro were tested. Results:The inhibition ratios of the 4 groups against Streptococcus mutans were 99%, 96%, 98%, and 90% in turn. The inhibition ratios of the 4 groups against Candida albicans were 91%, 82%, 90%, and 80% respectively. Conclusion: The antimicrobial effect of PMMA denture base containing silver-supported antimicrobial agents STR-1 of nanometer level at concentration of 5 mg/ml against Streptococcus mutans and Candida albicans in vitro is durable.