The effect of heat shock on the expression of urokinase-type plasminogen activator receptor in human tongue squamous cell carcinoma Tca 8113 cells
- VernacularTitle:热休克对人舌癌Tca8113细胞尿激酶型纤溶酶原激活物受体表达的影响
- Author:
Xinhua LIANG
;
Ge FENG
;
Dazhang WANG
;
Zuyi MAO
;
Weidong LENG
- Publication Type:Journal Article
- Keywords:
Urokinase-type plasminogen activator receptor;
Hyperthermia;
Tongue squamous cell carcinoma;
Invasion;
Metastasis
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the expression of urokinase-type plasminogen activator receptor (uPAR) in human tongue squamous cell carcinoma Tca 8113 cells at different dosages of heat shock. Methods:The expression of uPAR protein in Tca 8113 cells was examined using immunohistochemical technique (IH) and flow cytometry (FCM) after the cells had been treated at 37,40,43 or 45 ℃ for 40 min. Results:The fluorescent intensity of uPAR protein of Tca 8113 cells treated at 37,40,43 and 45 ℃ was 11.36?0.06,9.98?0.12, 10.37?0.05 and 11.31?0.10 respectively.Conclusion:Heat shock can reduce the expression of the uPAR protein of Tca 8113 cells.
