Expression of vascular cell adhesion molecule-1 in recurrent oral ulceration
- VernacularTitle:粘附分子在复发性口腔溃疡的发病机制中作用的探讨
- Author:
Rui SUN
;
Yu DONG
;
Haiying CHAO
;
Xiaozhen SUN
- Publication Type:Journal Article
- Keywords:
Aphthous stomatitis;
Vascular cell adhesion molecule-1;
Enzyme-linked immunosorbent assay
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of soluble vascular endothelial cell adhesion molecule-1(sVCAM-1) and soluble intercellular adhesion molecule-1 (sICAM-1) in recurrent oral ulceration (ROU). Methods: sVCAM-1 and sICAM-1 in oral menbrane tissue sampls were measured with an enzyme linked immunosorbent assay using sandwich technices in 45 patients with ROU and 40 nomal controls. Results: The expression level of sVCAM-1 in the oral membrane tissue samples of ROU patients was higher than that in the controls (P0.05). Both sVCAM-1 and sICAM-1 expression were not significantly different with the stages (ROU-active and ROU-free) of the lesion. Conclusion: sVCAM-1 might play a role in ROU.
