A randomized controlled clinical trial of full-spectrum endoscopy versus conventional colonoscopy for the diagnosis of colonic polyps
10.3760/cma.j.issn.1007-5232.2017.09.002
- VernacularTitle:全景内镜与普通肠镜诊断大肠息肉的随机对照研究
- Author:
Ronggui ZHANG
1
;
Qiyang HUANG
;
Xiuxue FENG
;
Meng LI
;
Enqiang LINGHU
Author Information
1. 解放军总医院消化内科
- Keywords:
Colonoscopy;
Full-spectrum endoscopy;
Intestinal polyps;
Adenoma
- From:
Chinese Journal of Digestive Endoscopy
2017;34(9):621-624
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic efficiency of full-spectrum endoscopy(FUSE) versus conventional colonoscopy for colonic polyps and adenoma. Methods Patients who underwent colonoscopy were randomly allotted into two groups according to randomization and self-control criteria. Patients in group A underwent conventional endoscopy firstly and then to FUSE. Patients in group B were opposite performed the examinations. The polyps and adenomatous polyps were resected or biopsied for pathological examination. Miss rate of colonic polyps as well as adenomatous polyps was calculated. Results A total of 100 patients were recruited for the study,including 45 in group A and 55 in group B. FUSE was significantly superior compared to conventional endoscopy with lower miss rate of polyps(6.52% VS 34.04%,χ2=17.685,P=0.000)as well as adenomatous polyps(5.00% VS 34.38%, χ2=11.774, P=0.001). For the first endoscopic examination,the adenomatous polyps which were found out by FUSE were more than that of ordinary colonoscopy in the right colon(χ2=5.153,P=0.023). The size of adenoma found by ordinary colonoscopy and FUSE was no statistically different whether in the first(t=0.334,P=0.739)or second(t=1.297,P=0.219)endoscopic examinations. Conclusion FUSE is useful to improve the quality of endoscopic examination because of its broad view-field.
