Research progress of nucleic acid detection in cerebrospinal fluid
10.3760/cma.j.issn.1009-9158.2017.12.004
- VernacularTitle:脑脊液核酸检测的研究进展
- Author:
Fang FANG
1
;
Guojun ZHANG
;
Wei LI
;
Xixiong KANG
Author Information
1. 100050,首都医科大学附属北京天坛医院神经系统单基因病诊断中心
- Keywords:
Cerebrospinal fluid;
Nucleic acids;
Sequence analysis,DNA;
Polymerase chain reaction;
Central nervous system diseases;
Tumor markers,biological
- From:
Chinese Journal of Laboratory Medicine
2017;40(12):920-923
- CountryChina
- Language:Chinese
-
Abstract:
The cerebrospinal fluid(CSF)is the most closely relatedbody fluidtocentral nervous system(CNS).Compared with other samples, CSF componentsare able to reflect the lesions of CNSmore directly.The detection of CSF pathogen nucleic acid is significantly better than the traditional detection method.Circulating tumor DNA(ctDNA)in CSF is very promising to be a diagnostic and monitoring marker for primary brain tumors and metastatic brain tumors.
