Clinical analysis of acute renal failure caused by urinary calculi obstruction in infants under the age of 6 months
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.2095-428X.2017.23.010
   		
        
        	
        		- VernacularTitle:6月龄以下婴儿泌尿系结石梗阻导致急性肾衰竭临床分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yidong HUANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Li ZENG
			        		
			        		;
		        		
		        		
		        		
			        		Xue MA
			        		
			        		;
		        		
		        		
		        		
			        		Jie ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Miao YUAN
			        		
			        		;
		        		
		        		
		        		
			        		Lei KANG
			        		
			        		;
		        		
		        		
		        		
			        		Wei SHAN
			        		
			        		;
		        		
		        		
		        		
			        		Guizheng HUANG
			        		
			        		;
		        		
		        		
		        		
			        		gang Lu HUANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 四川大学华西医院小儿外科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Urolithiasis;
			        		
			        		
			        		
				        		Obstruction;
			        		
			        		
			        		
				        		Renal failure,acute;
			        		
			        		
			        		
				        		Treatment;
			        		
			        		
			        		
				        		Hemodialysis;
			        		
			        		
			        		
				        		Infants
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Applied Clinical Pediatrics
	            		
	            		 2017;32(23):1793-1796
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To retrospectively summarize the diagnosis and treatment experience of acute renal failure caused by urinary calculi obstruction in infants under the age of 6 months in order to improve the level of treat-ment. Methods Between January 2010 and December 2014,15 infants under the age of 6 months with bilateral urinary tract calculi obstruction leading to acute renal failure were treated in West China Hospital,Sichuan University. All cases were Tibetan(10 males,5 females). The ages ranged from 1 month 15 days to 5 months 24 days. The weights ranged from 3. 5 to 7. 0 kg. The clinical characteristics,treatment and clinical outcome were analyzed. Results A total of 9 infants(5 males,4 females)were assessed to be able to tolerate general anesthesia surgery and received positive conservative treatment before operation,and obstruction relief within 6 hours of admission. Six infants (5 males, 1 female)with serious internal milieu disorder,pneumonia,and shock,were assessed as critical cases,who could not tolerate general anesthesia surgery temporarily. Under the emergency blood purification support,they received anti -infection,spasmolysis,rehydration,to correct the internal milieu disorder and obstruction relief within 12 hours of admis-sion. Serum potassium,creatinine returned to normal 12 - 48 hours after obstruction relief. Stone specimens were obtained from 5 cases,and the stone compositions were calcium oxalate stone in 3 cases,calcium oxalate and carbonate apatite mixed stone in 2 cases. A total of 13 cases need further urolithiasis treatment. Conclusions The infants under the age of 6 months with bilateral urinary tract calculi obstruction are more severe with more complications. The emergency treatment principle is to save lives,then relieve the obstruction;surgery should be as brief as possible,since removing the stones is not the primary purpose. If the infants are in critical,life - threatening circumstances,and cannot tolerate general anesthesia surgery,the blood purification will be helpful to gain time and create conditions for treatment.