Comparison of clinical value of ELISA and cold agglutination test in diagnosis of early diagnosis of Myco-plasma pneumoniae infection
10.3969/j.issn.1006-5725.2017.23.035
- VernacularTitle:酶联免疫吸附试验与冷凝集试验对诊断早期肺炎支原体感染的临床价值比较
- Author:
Xiangwei HUANG
1
;
Xia XU
;
Jingjing GUO
;
qun Hong TAO
Author Information
1. 325027,温州医科大学附属第二医院医学检验中心
- Keywords:
Mycoplasma pneumoniae(MP);
Enzyme linked immunosorbent assay(ELISA);
Cold agglutination test;
fever
- From:
The Journal of Practical Medicine
2017;33(23):3987-3989
- CountryChina
- Language:Chinese
-
Abstract:
Objective Comparison of ELISA for detection of Mycoplasmapneumoniae IgM(MP-IgM)and cold agglutination test for early diagnosis of Mycoplasma pneumoniae infection in clinical value. Methods ELISA and cold agglutination test were used to detect 500 cases of serum samples infected with Mycoplasma pneumoniae. Results The positive rate of ELISA(54.8%)was significantly higher than that of cold agglutination(28.4%), and there was significant difference(χ2=71.72,P<0.01).The positive rates of ELISA in Fever 3 days(44.2%), 4~7days(46.4%),8~14 days(71.3%),and 15 days(78.6%)were significantly higher than that of cold aggluti-nation 22.1%,25.4%,35.7%,35.7%.The positive rates were increased with fever days extended.These is no sig-nificant difference(P > 0.05)in 1 ~ 3 days and 4 ~ 7 days,8~14 days and more than 15 days(P > 0.05) by ELISA,while there was a significant difference(P < 0.05)in 8~14 days with 1 ~ 3 days and 4 ~ 7 days. Conclution ELISA of detection MP-IgM should be selected prior in clinical detection,especially in the fever 8~14 days.It can obviously improve the early detection rate of mycoplasma infection and give the most useful value for clinical diagnosis.
