Study on Optimization Supercritical CO2Extraction Technology of Paniculate Swallowwort Root by Design-response Surface Method
10.3870/j.issn.1004-0781.2018.01.022
- VernacularTitle:星点设计-效应面法优选徐长卿超临界二氧化碳萃取工艺
- Author:
Quanwei YANG
1
;
Lu CHENG
;
Geng ZHANG
;
Song HU
Author Information
1. 武汉市第一医院药学部
- Keywords:
Paniculate swallowwort;
Paeonal;
Design-response surface method;
Extraction;
CO2;
supercritical;
Chromatography;
high performance liquid
- From:
Herald of Medicine
2018;37(1):85-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the supercritical CO2extraction technology condition of radix cynanchi paniculati. Methods The paeonol extract was used as indexes.The content of paeonol was determined by high performance liquid chromatography method.The extraction condition was optimize tby design-response surface method. Results The optimum process conditions for the extraction pressure was 10.81 MPa,extraction temperature was 55 ℃,flow rate of CO2was 59.91 L·h-1,extraction time was 2.42 h. Conclusion The content of paeonol with optimum extraction process of radix cynanchi paniculati is high,process is stable and feasible.
