A Case of Mucormycosis Involving the Skin in Renal Transplant Recipient.
- Author:
Min Sun JEE
1
;
Hye Jin CHOI
;
Jee Ho CHOI
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
Author Information
1. Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. helena74@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Mucormycosis;
Renal transplantation;
Skin
- MeSH:
Anti-Bacterial Agents;
Antiviral Agents;
Blister;
Blood Vessels;
Cough;
Dermis;
Diabetes Mellitus;
Emergency Service, Hospital;
Fever;
Fungi;
Hematologic Diseases;
Humans;
Hyphae;
Kidney Transplantation;
Lower Extremity;
Middle Aged;
Mucormycosis*;
Opportunistic Infections;
Organ Transplantation;
Purpura;
Renal Insufficiency;
Respiratory Insufficiency;
Shock, Septic;
Skin*;
Transplantation*;
Transplants;
Vital Signs
- From:Korean Journal of Dermatology
2003;41(4):501-504
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mucormycosis is a rare and opportunistic infection usually associated with hematologic diseases, diabetes mellitus, renal failure, solid tumors, and organ transplantations. We present here a considered case of disseminated mucormycosis in renal transplant recipient. A 60-year-old man who had undergone second kidney transplantation for a month visited emergency room due to 5 day history of cough with spiking fever and abnormal mental status and vital signs were rapidly deteriorated. Septic shock was suspicious. He was admitted to ICU and treated with broad spectrum antibiotics and antiviral agents, but there was no improvement. A few days later, several large hemorrhagic blisters and purpura occurred on the face, trunk, and both lower extremities. The histopathologic examination from skin specimen revealed large, broad, nonseptate hyphae branched at right angles in the dermis and blood vessels, which was consistent with mucormycosis. But the skin culture for fungus was negative. He had had no skin trauma history and evidence. So we considered the disseminated mucormycosis from unknown primary origin. He died of progressive respiratory failure before antifungal treatment.
