Research progress of heat shock protein 70 in hepatocellular carcinoma
10.11904/j.issn.1002-3070.2017.06.009
- VernacularTitle:热休克蛋白70在肝细胞癌中的研究进展
- Author:
Lingyun ZHAO
1
;
广西医科大学 南宁 530021
;
Lunan QI
Author Information
1. 广西医科大学附属肿瘤医院肝胆外科 南宁 530021;广西医科大学 南宁 530021
- Keywords:
Heat shock protein 70;
Hepatocellular carcinoma;
Diagnosis;
Prognosis
- From:
Practical Oncology Journal
2017;31(6):528-532
- CountryChina
- Language:Chinese
-
Abstract:
Heat shock protein 70(HSP70)is a highly conserved polypeptide protein,which plays an im-portant role in protein homeostasis,apoptosis,invasion and cell signaling transduction. Many studies have shown that the expression level of HSP70 is closely related to the development and progression of tumor,which is a low expression in normal tissues and the overexpression in tumor tissue. Hepatocellular carcinoma ( HCC ) is con-cealed,and the related study reported that the expression of HSP70 can be used as a sensitive biological index for the diagnosis and differential diagnosis for early HCC,and also affects the treatment and prognosis of patients with HCC. This article will summary the relationship between the expression of HSP70 and HCC.
