Research Progress in Tacrolimus Used in Children with Refractory Nephrotic Syndrome
- VernacularTitle:他克莫司治疗儿童难治性肾病综合征的研究进展
- Author:
Ran LI
1
;
Huawen XIN
Author Information
1. 解放军武汉总医院临床药理科 武汉430070
- Keywords:
Tacrolimus;
Immunosuppressant;
Children;
Refractory nephrotic syndrome
- From:
China Pharmacist
2017;20(12):2228-2232
- CountryChina
- Language:Chinese
-
Abstract:
Tacrolimus is a kind of calcineurin inhibitor ( CNI) , and it is a novel immunosuppressant with similar efficacy to ciclos-porin. This paper reviewed the recent advances in the treatment of refractory nephrotic syndrome in children with tacrolimus, including the comparison of efficacy, dosage, adverse effects and clinical evaluation with the other immunosuppressive agents such as ciclosporin and mycophenolate mofetil in order to provide reference for clinics.
