Clinical characteristics and prognostic factors of pelvic chondrosarcoma
10.3969/j.issn.1674-8115.2017.11.016
- VernacularTitle:骨盆软骨肉瘤临床特点和预后因素分析
- Author:
wu Qi ZHAO
1
;
zhuang Ji WANG
;
bin Wei ZHANG
;
hui Yu SHEN
;
Rong WAN
Author Information
1. 上海交通大学 医学院附属瑞金医院骨科
- Keywords:
pelvic chondrosarcoma;
prognostic factors;
tumor recurrence
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2017;37(11):1541-1546
- CountryChina
- Language:Chinese
-
Abstract:
Objective· To summarize the clinical characteristics and prognostic factors of pelvic chondrosarcoma. Methods · A total of 73 cases of chondrosarcoma were collected, including 24 of pelvic. The clinical characteristics and prognostic factors of pelvic chondrosarcoma were analyzed by statistic methods. Results · The ratio of men to women was 1.4:1,and the median age is 43.5 years old. According to the classification of pelvic proposed by Enneking, there were 5 in region Ⅰ?, 14 in region Ⅱ?, and 5 in region Ⅲ?. On histological review, 1 was grade 1, 15 were grade 2 ,and 8 were grade 3. The histologic types included 17 conventional, 3 dedifferentiated, 2 secondary, and 1 mesenchymal. The overall survival rates of pelvic chondrosarcoma were (82.2±8.1) %,(77.3±8.9) % and(52.4±12.1) % for 3, 5 and 10 years respectively. Local recurrence rate of pelvic chondrosarcoma (83.3%) was significantly higher than those of other sites(34.7%)(P=0.000),and the proportion of amputation was significantly higher than the other sites(50.0% vs 20.4%, P=0.000), but there was no significant difference in the overall survival between the two groups (P=0.216). Conclusion · Pelvic chondrosarcoma have a higher local recurrence rate than the other sites and is tend to result in amputation. Early local recurrence after surgery indicates poor prognosis.
