Preliminary investigation on diagnostic value of polyethylene glycol precipitation and gel filtration chromatography in insulin autoimmune syndrome
10.3760/cma.j.issn.1000-6699.2017.09.008
- VernacularTitle:应用聚乙二醇沉淀法及凝胶层析分离法诊断胰岛素自身免疫综合征的价值探讨
- Author:
Jing KONG
1
;
Han ZHANG
;
Junlin FU
;
Ge LI
;
Qian ZHANG
;
Ming LI
;
Xinhua XIAO
;
Ou WANG
;
Lian DUAN
Author Information
1. 浙江大学医学院附属第二医院内分泌科
- Keywords:
Insulin autoimmune syndrome;
Hypoglycemia;
Polyethylene glycol precipitation;
Gel filtration chromatography
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(9):748-751
- CountryChina
- Language:Chinese
-
Abstract:
A 65-year-old male presented with recurrent palpitation and fatigue over one year. Lab tests revealed him with hyperinsulinaemic hypoglycemia. Insulin autoimmune antibody was repeatedly negative. Imaging of the pancreas seemed to be normal. Insulin-insulin autoimmune antibody complexes were detected by polyethylene glycol precipitation and gel filtration chromatography, thus the diagnosis of insulin autoimmune syndrome was suggested. By adjusting diet and administration of acarbose, all the symptoms were evidently relieved.
