Effect of restrictive intravenous fluid on the complications and quality of life in the advanced hepatocellular carcinoma patients
10.3760/cma.j.issn.1008-1372.2017.09.009
- VernacularTitle:限制性输液对晚期肝癌并发症及患者生存质量的影响
- Author:
Yong LI
1
;
Yan HUANG
;
Songlin HOU
;
Lixin ZHANG
;
Jiali LI
;
Lu YANG
;
Xiaoqiong LI
;
Zhengru CHEN
;
Zhengwei LENG
;
Jingdong LI
Author Information
1. 川北医学院附属医院普外科
- Keywords:
Fluid therapy;
Liver neoplasms/CO/PC;
Quality of life
- From:
Journal of Chinese Physician
2017;19(9):1313-1316
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of restrictive intravenous fluid on the complications and quality of life in the advanced hepatocellular carcinoma patients.Methods Clinical data of Three hundred and fifty-seven cases with advanced hepatocellular carcinoma from Mar 2010 to Mar 2016 was retrospectively analyzed.One hundred and sixty-eight cases were recruited in the restrictive intravenous fluid (RIF) group,and One hundred and eighty-nine cases were involved in the control group.The average volume of intravenous fluid of each day,plasma albumin concentration,splanchnocoel hydrops rate,phlebitis,incidence of vomiting,cancer related pain degree,anxiety degree were compared in the two groups.Results The average volume of intravenous fluid of each day in the RIF group [(720.29 ± 106.84) ml] were much lower than that in the control group [(1 820.36±342.12)ml] (P ＜0.05).The plasma albumin concentration in the RIF group [(35.65 ± 2.21)g/L] were higher than that in the control group [(32.25 ±2.32)g/L] (P ＜0.05).The rate of splanchnocoel hydrops,phlebitis,vomiting,bedsores,and hypstatic pneumonia in RIF group were 6.25％,4.69％,8.59％,3.9％,11.72％ and those in the control group were 13.97％,10.92％,17.47％,10.04％,and 24.45％,respectively (P ＜ 0.05).Moreover,the scores of cancer related pain and anxiety were much lower in the RIF group (5.21 ± 1.09,39.12 ± 5.54) than those in the control group(5.68 ± 1.18,41.56 ± 6.78) (P ＜ 0.01).Conclusions Restrictive intravenous fluid therapy can decrease the cancer associated complications and improved the quality of life in the advanced hepatocellular carcinoma patients.
