Meta-analysis of the value of DCE-MRI in the diagnosis of benign and malignant solitary pulmonary nodules
10.3969/j.issn.1002-1671.2017.10.010
- VernacularTitle:DCE-MRI对孤立性肺结节良恶性诊断价值的Meta分析
- Author:
Chuan LIU
1
;
Li ZHU
;
Mengjie CAI
;
Lang WANG
;
Xiaofeng JIANG
;
Licheng LEI
;
Chuan ZHANG
;
Bing LI
;
Hanfeng YANG
;
Xiaoxue XU
Author Information
1. 川北医学院附属医院放射科
- Keywords:
solitary pulmonary nodule;
dynamic contrast-enhanced magnetic resonance imaging;
Meta-analysis
- From:
Journal of Practical Radiology
2017;33(10):1531-1536
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of dynamic contrast-enhanced MRI (DCE-MRI)in diagnosing benign and malignant solitary pulmonary nodule (SPN)with Meta-analysis.Methods The databases including PubMed,EBSCO,Cochrane Library,Ovid, CBM,VIP,Wan Fang Database and CNKI were searched to select the literatures about the diagnosis of SPN with DCE-MRI.Inclusion criteria were established,according to the validity criteria for diagnostic research published by the Cochrane Methods Group on Screening and Diagnostic Tests .Methodological quality was assessed by using the quality assessment of diagnostic studies (QUADAS-2)instrument.Meta-analysis was performed by Stata 12.0 and Meta-Disc 1.4.According to the results of heterogeneity of the included articles,proper effect model was selected to calculate the pooled sensitivity,specificity,positive likelihood ration,negative likelihood ration,and diagnostic odds ratio.Summary receiver operating characteristic (SROC)curve was drawed and the area under the curve (AUC)was calculated.Results A total of 17 studies involving 1255 lesions were included.The results of Meta-analysis showed the pooled sensitivity,specificity,positive likelihood ration,negative likelihood ration,and diagnostic odds ratio were 0.95,0.81,4.9,0.06 and 85,respectively.The AUC of SROC was 0.97.Conclusion DCE-MRI has relatively high sensitivity and specificity in the differential diagnosis of benign and malignant SPN.
