Comparative analysis of influenza etiology surveillance in general hospital and children′s hospital
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1673-4130.2017.19.019
   		
        
        	
        		- VernacularTitle:综合医院和儿童专科医院流感病原学监测结果比较分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Da LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Sen WANG
			        		
			        		;
		        		
		        		
		        		
			        		Jingbo ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Yongquan WANG
			        		
			        		;
		        		
		        		
		        		
			        		Shuyuan BAI
			        		
			        		;
		        		
		        		
		        		
			        		Jingjing PANG
			        		
			        		;
		        		
		        		
		        		
			        		Xilong AN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 北京市西城区疾病预防控制中心
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		general hospital;
			        		
			        		
			        		
				        		children′s hospital;
			        		
			        		
			        		
				        		etiological surveillance
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			International Journal of Laboratory Medicine
	            		
	            		 2017;38(19):2709-2711,2714
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective By comparing and analyzing the etiological monitoring results of influenza in Xicheng District general hos-pital and children′s Hospital ,to explore the epidemic regularity of influenza in children ,so as to provide the basis for developing in-fluenza prevention and control measures .Methods A total of 40 swabs of influenza samples were collected every week from two sentinel hospitals ,and the virus RNA was extracted and detected by RT-PCR method .Results There was a statistically significant difference in positive rate of influenza pathogen surveillance between general hospitals and children′s hospitals (21 .8% vs .14 .9% ) (P<0 .001) .In the general hospital ,the positive rate was highest in people aged ≥60 years old(31 .3% ) .In the children′s hospital , the positive rate was highest in people aged >4—14 years old(26 .7% ) .Both hospitals had an epidemic peak of influenza from No-vember to December of next year ,it was typical influenza epidemic of the North area .But the children′s hospital had a epidemic trough in January and February .In both hospitals ,the circulating strains were H3 ,H1N1 ,type B ,the predominant type was H3 and type B .Conclusion Taking the general hospital as a reference ,the quality of influenza surveillance in the children′s hospital was relatively stable and reliable .Lack of the people aged >24— <60 years old and aged ≥60 years old in children′s hospital ,is the key reason of the statistically significant difference of the positive rate ,between the general hospital and the children′s hospital .Chil-dren′s influenza vaccination rate is higher than the other age group ,and the protective effect of vaccine is better .