A Case of Non-Functioning Huge Adrenocortical Carcinoma Extending Into Inferior Vena Cava and Right Atrium.
10.3346/jkms.2006.21.3.572
- Author:
Kye Hun KIM
1
;
Jong Chun PARK
;
Sang Yup LIM
;
Il Suk SOHN
;
Kyung Ho YUN
;
Sang Hee CHO
;
Young Joon HONG
;
Hyung Wook PARK
;
Ju Han KIM
;
Weon KIM
;
Young Keun AHN
;
Ik Joo CHUNG
;
Myung Ho JEONG
;
Jeong Gwan CHO
;
Jung Chaee KANG
Author Information
1. Department of Cardiovascular Medicine, Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea. jcpark@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Adrenocortical Carcinoma;
Neoplasm Metastasis;
Vena Cava, Inferior
- MeSH:
Vena Cava, Inferior/*pathology;
Tomography, X-Ray Computed;
Remission Induction;
Neoplasm Metastasis;
Male;
Humans;
Heart Neoplasms/pathology/*secondary;
Heart Atria/*pathology;
Follow-Up Studies;
Echocardiography;
Biopsy;
Adult;
Adrenocortical Carcinoma/*diagnosis/*pathology;
Adrenal Cortex Neoplasms/*diagnosis/*pathology
- From:Journal of Korean Medical Science
2006;21(3):572-576
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary adrenocortical carcinoma (ACC) is a rare tumor and its usual sites of metastasis are the lung (71%), lymph node (68%), liver (42%), and bone (26%). However, intracaval invasion extending into the right atrium is very rare and spontaneous regression of tumor burden in adrenal carcinoma is also rare. We report a case of ACC with direct invasion of the inferior vena cava and right atrium. A 34-yr-old male patient presented with progressive dyspnea, weight loss, and poor oral intake over 3 months. Non-functioning ACC with direct invasion of the inferior vena cava and right atrium was confirmed by imaging, pathologic, and hormonal study. Chemo-radiotherapy was attempted. However, tumor burden was not changed, but rather toxic hepatitis and thrombocytopenia were developed. His subjective symptoms and general conditions were improved after 1 month of conservative management and the patient was discharged. During clinical follow-up, this tumor showed spontaneous regression.
