A Case of Functioning Paraganglioma Mimicking Anaphylactic Shock: A Case Report.
10.4266/kjccm.2013.28.2.152
- Author:
Ju Young HAN
1
;
Oh Hyun LEE
;
Gyung Eun KIM
;
Seung Baik HAN
;
So Hun KIM
;
Moonsuk NAM
;
Yong Seong KIM
;
Seongbin HONG
Author Information
1. Department of Internal Medicine, Division of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea. sbhongmd@inha.ac.kr
- Publication Type:Case Report
- Keywords:
midazolam;
paraganglioma;
shock
- MeSH:
Anaphylaxis;
Arrhythmias, Cardiac;
Blood Pressure;
Chromaffin Cells;
Colonoscopy;
Conscious Sedation;
Headache;
Heart Failure;
Humans;
Hypertension;
Hypotension;
Male;
Midazolam;
Myocardial Infarction;
Paraganglioma;
Pheochromocytoma;
Pulmonary Edema;
Shock;
Tachycardia
- From:The Korean Journal of Critical Care Medicine
2013;28(2):152-155
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paraganglioma is a tumor originating from the extra-adrenal chromaffin cells, and functional paraganglioma causes paroxysmal hypertension, headache and tachycardia, due to excess excretion of catecholamine. However, rarely, ARDS, acute myocardial infarction, heart failure, arrhythmia, and pulmonary edema are also seen in patients with paraganglioma and clinical manifestations are depending on the patient's intravascular volume status. Seventy one-years-old male was presented with hypotension and pulmonary edema after intravenous midazolam injection during colonoscopy under conscious sedation. The patient was initially suspected with anaphylactic shock, due to midazolam injection. However, later, he was diagnosed with paraganglioma, and blood pressure was successfully controlled with alpha adrenergic blockade. We suggest that when we encounter heart failure, pulmonary edema and shock of unknown origin, pheochromocytoma must be taken into consideration.
