Association between Dopamine Receptor D4 Gene Polymorphism and Obsessive-Compulsive Disorder
- VernacularTitle:多巴胺D4受体基因与强迫症的关联
- Author:
yong, XU
;
zhen, WANG
;
ze-ping, XIAO
;
dong-xiang, WAN
;
yi-ping, QIANG
;
san-duo, JIANG
- Publication Type:Journal Article
- Keywords:
obsessive-compulsive disorder;
gene;
dopamine receptor D4;
polymorphism
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). After dividing the patients into early-onset and late-onset subgroups, there were significant differences of DRD4 genotype and allele frequency between early-onset patients and controls (P0.05). Conclusion The results suggested that the polymorphism of DRD4 receptor gene may be associated with early-onset OCD. The 3/4 genetype may be the risk factor of early-onset OCD. Early-onset and late-onset OCD may have different etiology.
