Influence of Sedation and Analgesia on Stress Reaction of Post-Operation Infants with Congenital Heart Disease
- VernacularTitle:镇静镇痛对先天性心脏病婴幼儿术后应激反应的影响
- Author:
jian-hui, ZHANG
;
zhao-hui, CAI
;
jie, HONG
;
tu-xun, SI
;
xiao-yuan, ZHAO
- Publication Type:Journal Article
- Keywords:
sedation;
analgesia;
stress reaction;
congenital heart disease;
infant
- From:Journal of Applied Clinical Pediatrics
2006;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate influence of sedation and analgesia on stress reaction of post-cardiac surgery in infants with congenital heart disease.MethodsForty children with congenital heart disease were randomly divided into 2 groups after cardiac surgery.The analgesia group was given 0.5-2.0 ?g/(kg?h) fentanyl intravenous infusion in 20 children undergoing cardiovascular surgery.The control group was given 5-8 mg/(kg?dose) lbuprofen orally.Midaiolam 0.01-0.20 mg/(kg?h) was used in 2 groups for sedation by intravenous infusion or 0.05-0.10 mg/(kg?dose)by intravenous push intermittently.The effects and adverse effects of sedation and analgesia were observed on 2,8,24,48 h after surgery in each group.The levels of cortisol,growth hormone,insulin and blood glucose were measured,respectively.ResultsThere were significant differences in Ramsay,Comfort value on 2,8,24 h(Pa
