Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report.
10.14791/btrt.2017.5.1.37
- Author:
Jae Young KIM
1
;
Tae Young JUNG
;
Kyung Hwa LEE
;
Seul Kee KIM
Author Information
1. Department of Neurosurgery, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Korea. jung-ty@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Hemorrhage;
Astrocytoma;
Tuberous sclerosis;
Surgery
- MeSH:
Astrocytoma*;
Brain;
Cerebral Ventricles;
Child;
Cytoplasm;
Diagnosis;
Eosinophils;
Female;
Follow-Up Studies;
Glial Fibrillary Acidic Protein;
Headache;
Hemorrhage*;
Humans;
Magnetic Resonance Imaging;
Recurrence;
Tuberous Sclerosis;
Ventricular Septum
- From:Brain Tumor Research and Treatment
2017;5(1):37-41
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages. The origin of the mass was identified as the ventricular septum adjacent to the foramen of Monro. A pathological analysis revealed pleomorphic multinucleated eosinophilic tumor cells with abundant cytoplasm. These cells showed positive staining for the glial fibrillary acidic protein and S100 protein. A diagnosis of SEGA was established. The patient recovered without any neurological symptoms. There was no evidence of TSC. The radiological follow-up showed no recurrence for 2 years. This was a case of SEGA with intratumoral hemorrhage, for which a favorable outcome was achieved, without any neurological deficit after tumoral resection.
