Heterotopic ossification in skeletal muscle metastasis from colonic adenocarcinoma--a case report.
- Author:
Venkatesh R Naik
;
Hasnan Jaafar
;
Samarendra S Mutum
- Publication Type:Journal Article
- MeSH:
Adenocarcinoma;
Muscle, Skeletal;
Heterotopic;
Neoplasm Metastasis;
Mass, NOS
- From:The Malaysian journal of pathology
2005;27(2):119-21
- CountryMalaysia
- Language:Malay
-
Abstract:
Colonic adenocarcinoma metastasising to the skeletal muscle is rare. A-56-yr-old Malay man was diagnosed to have adenocarcinoma of the right colon [Dukes B] for which a right hemicolectomy was performed, followed by radiotherapy and chemotherapy. Five years later the patient presented with a mass in the rectus abdominis muscle. The serum carcinoembryonic antigen was 71 ng/Ml. The mass was resected. Gross and microscopical examination showed multiple deposits of mucin-secreting adenocarcinoma with prominent heterotopic ossification in the stroma. The exact pathogenesis and significance of heterotopic ossification is not clear, but bone morphogenetic proteins may play an important role.
