Analysing result of cytogenetic tests in 24 patients with hypospadias in comparison with clinical and surgical diagnosis
- Author:
Phan Thi Hoan
- Publication Type:Journal Article
- Keywords:
Hypospadias
- MeSH:
Hypospadias;
Diagnosis;
Surgery;
Cytogenetics
- From:Journal of Practical Medicine
2005;503(2):33-35
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Analysing cytogenetic charateristics of 24 patients with hypospadias in Vietnam National Hospital of Pediatrics from January to December 1998, comparing with clinical and surgical diagnosis. 3 children were found with chromosomal aberrations. All these children had peripheral hypospadias , 2 out of 3 children had bilateral undescend testes, 1 child had unilateral undescend testes. Chromosomal test found that: 1 child had mosaicism 46,XX(90%)/47XXY(10%); Barr bodies 8%, 2 children had 46,XX males, 1 out of these 2 children had plastic surgery for male urethra. The results of Barr bodies tests were corresponded to karyotypes. If karyotype is 46,XY, Barr bodies tests are negative; if karyotype is 46,XX, Barr bodies tests are positive
