Randomized Clinical Trial of Periarticular Drug Injection used in combination Patient-Controlled Analgesia versus Patient-Controlled Analgesia Alone in Total Knee Arthroplasty
- Author:
MN Sabran
;
AJM Talha
;
M Omar
;
MY Ibrahim
;
Y Shahril
- Publication Type:Journal Article
- Keywords:
Total knee arthroplasty, periarticular drug injection, Ropivacaine, peri-operative analgesia
- From:Malaysian Orthopaedic Journal
2008;2(2):21-26
- CountryMalaysia
- Language:English
-
Abstract:
This is a prospective randomized clinical trial to compare use of a combination of periarticular drug injection with patientcontrolled analgesia (PCA) to PCA alone in post-total knee arthroplasty (TKA). Thirty patients who were admitted for unilateral total knee arthroplasty were selected randomly into an Injection group or a Standard group. The periarticular injection contained Ropivacaine, Ketorolac and Adrenaline, given intra-operatively. The mean amount of opioid used was
22.87 mmol/L in the Injection group as compared to 39.78
mmol/L in the Standard group (p = 0.026). The Injection
group had lower pain score at rest and during exercise
(p=0.021, p=0.041, respectively), as well as better return to function (p=0.026) and shorter hospital stay (6.1 days,
Injection; 7.5 days, Standard, p=0.027). Overall, the group
receiving periarticular drugs injection had less pain, less
narcotic usage, earlier return to function, similar experience of adverse effects and shorter hospital stays.
- Full text:W020151222404313568971.pdf
