Clinicopathologic characteristics and treatment of medullary thyroid carcinoma

VernacularTitle:甲状腺髓样癌的临床病理特征及治疗
Author: Donghang HUANG ; Huashui LI ; Ailong ZHANG ; Hang WANG ; Lizhen QIU ; Qiang LIN ; Zhenhui YOU
Publication Type:Journal Article
Keywords: Thyroid neoplasms; Medullary carcinoma
From: Journal of Endocrine Surgery 2013;7(4):275-277
CountryChina
Language:Chinese
Abstract: Objective To explore the clinicopathologic characteristics and treatment of medullary thyroid carcinoma(MTC).Methods The data of 42 cases of MTC admitted to Fujian Medical University Provincial Clinical College from Jan 1995 to Feb 2010 were retrospectively analyzed.Surgery was performed in all the 42 cases.All were proved to be MTC by pathology.Results Surgery was performed in all the 42 cases.All were proved to be MTC by pathology.The lymph node metastasis rate was 76.19％ (32/42).The central lymph node metastasis rate was 61.90％ (26/42).All the 42 cases were followed up for 1 to 502 months with 102 months as the median.35 cases(83.33％)were followed up for more than 5 years and the 5-year overall survival rate was 85.71％ (30/35).Death occurred in 5 cases.Conclusions The lymph node metastasis rate of MTC is high.The treatment should be based on the principle of radical resection.Total thyroidectomy should be recommended to treat primary tumor.Lymph node dissection should be as thorough as possible.Central compartment neck dissection should be done in all cases.