Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer
10.3760/cma.j.issn.1674-6090.2015.02.006
- VernacularTitle:乳腺癌内乳前哨淋巴结活检新型示踪技术验证研究
- Author:
Binbin CONG
;
Pengfei QIU
;
Guoren YANG
;
Yanbing LIU
;
Tong ZHAO
;
Peng CHEN
;
Xiaoshan CAO
;
Chunjian WANG
;
Zhaopeng ZHANG
;
Xiao SUN
;
Yongsheng WANG
- Publication Type:Journal Article
- Keywords:
Breast Cancer;
Internal Mammary;
Sentinel Lymph Node Biopsy;
Visualization rate
- From:
Journal of Endocrine Surgery
2015;(2):109-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective To verify the accuracy of the modified technique for internal mammary sentinel lymph node biopsy ( IM-SLNB) in breast cancer .Methods In the validation study , the radiotracer was injected with the modified technique , and fluorescence tracer was injected into the peritumoral breast tissue .The radioac-tive IM-SLN was identified by preoperative lymphoscintigraphy and γprobe.The radioactive IM-SLN received bi-opsy during operation .The status of the fluorescence tracer was identified by the fluorescence imaging system . Results A total of 162 patients were enrolled from Sep .2013 to Dec.2014.IM-SLNB was performed in 110 pa-tients.The radiotracer and the fluorescence tracer were identified in the same IM-SLN in 94 cases, and the con-cordance rate was 85.5%(Case-base, Spearman coefficient correlation 0.823, P<0.001).Conclusion Dif-ferent tracers injected into the different sites of the intra-parenchyma can reach the same IM-SLN, proving the ac-curacy of the modified technique and the hypothesis of IM-SLN lymphatic drainage pattern ( IM-SLN receives not only the lymphatic drainage from the primary tumor area but the entire breast parenchyma ) .
