Multiple-electrode radiofrequency ablation via switching system in treating early-stage hepatocellular carcinoma
10.3760/cma.j.issn.1008-1372.2017.06.004
- VernacularTitle:转换器介导下多电极射频消融治疗早期肝细胞癌
- Author:
Guangliang HUANG
;
Jia LUO
;
Xi DING
;
Xiaoer ZHANG
;
Baoxian LIU
;
Manxia LIN
;
Ming KUANG
;
Xiaoyan XIE
- Keywords:
Carcinoma,hepatocellular/TH;
Catheter ablation/AE;
Equipment and supplies
- From:
Journal of Chinese Physician
2017;19(6):810-812,816
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively compare the safety and local efficacy of multiple-electrode switching based radiofrequency ablation (RFA) and the conventional RFA in treating single early-stage hepatocellular carcinoma (HCC).Methods A total of 82 patients with single early-stage HCC received either RFA with a multiple-electrode switching system (n =43) or conventional RFA (n =39) as the first-line treatment.The rate of initial local complete response,major complications and local tumor progression (LTP) were compared between two groups.Results The total ablation time was significantly shorter in the switching-RFA group [(16.7 ± 3.4) mins] than in the conventional RFA group [(29.8 ± 10.4) mins] (P ＜ 0.05).The rate of initial local complete response was 100％ (43/43) in the switching-RFA group and 94.9％ (37/39) in the conventional RFA group (P ＞0.05).After a mean follow-up period of (26.4 ± 21.8)months (ranging 3.0-91.6 months),the rates of LTP in the switching-RFA group and conventional RFA group were 16.3％ (7/43) and 17.9％ (7/39),respectively.The LTP rates in two groups were 16.1％ versus 11.2％ atyear1,and20.5％ versus 20.6％ at year2 (P=0.666).Conclusions The multiple-electrode switching based RFA is safe and effective with shorter ablation time in treating single early-stage hepatocellular carcinoma.
