Progresses of magnetic resonance spectroscopy in thalamo-cortical network of juvenile myoclonic epilepsy
10.13929/j.1003-3289.201607060
- VernacularTitle:青少年肌阵挛癫痫丘脑—皮质网络的磁共振波谱研究进展
- Author:
Lipei CAO
;
Zhengge WANG
;
Bing ZHANG
- Keywords:
Juvenile;
Epilepsies,myoclonic;
Magnetic resonance spectroscopy;
Thalamo-cortical network
- From:
Chinese Journal of Medical Imaging Technology
2017;33(6):954-958
- CountryChina
- Language:Chinese
-
Abstract:
Juvenile myoclonic epilepsy (JME) diagnosed with seizure history,semiology and electroencephalography is a syndrome of idiopathic generalized epilepsy.MRS can quantitatively detect the concentration of neurometabolites noninvasively,and assess the metabolic changes in brain.Currently,studies of pathogenesis of JME are focused on the dysfunction of thalamo-cortical network and the neurometabolites and imbalance of Glutamate and γ-aminobutyric acid in the network are alterted.Epilepsy is associated with the imbalance of the ratio of excitatory and inhibitory amino acid,and seizures lead to neuronal lesions which result in altered concentration of neuron related metabolites.This article reviewed MRS studies of JME by combining material metabolism,neural structure and function.
