Effect of determination of metals in Cardeniajasminoides Ellis by ICP-MS from online internal standard solution
10.7501/j.issn.1674-6376.2017.04.012
- VernacularTitle:在线内标浓度对电感耦合等离子体质谱法测定栀子金属元素的影响
- Author:
Yali ZHANG
;
Wei SUN
;
Lei ZHANG
;
Mingpeng MAO
;
Zhengliang YE
- Keywords:
online internal standard;
ICP-MS;
Cardeniajasminoides Ellis;
matrix effect
- From:
Drug Evaluation Research
2017;40(4):500-505
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide a proper concentration of Internal Standard Solution by comparing five different degrees to the simultaneous analysis of 10 metals including V,Cr,Mn,Fe,Ni,Cu,As,Cd,Pb and Hg in Cardeniajasminoides.Method An Inductively Coupled Plasma-Mass Spectrometry method with Microwave-Assisted Digestion was developed with10,50,200,500,1 000 μg/L of Ge,In,Bi as internal standard.Result The degree of 500 μg/L concentration of internal stand solution can both correct the matrix effect and alleviate the contamination as the 1 000 μg/L.Conclusion With excellent detection limits,high sensitivity and wide linear range,the 500 μg/L internal standard may serve as reference in the determination of elements in other traditional Chinese medicine (TCM).
