Animal models of cerebral venous and sinus thrombosis
10.3760/cma.j.issn.1673-4165.2017.03.016
- VernacularTitle:脑静脉窦血栓形成的动物模型
- Author:
Ying WEI
;
Xinbin GUO
;
Sheng GUAN
;
Xin DENG
;
Zibo WANG
;
Xiaoke LU
;
Yanhua DONG
- Keywords:
Sinus Thrombosis;
Intracranial;
Venous Thrombosis;
Disease Models;
Animal
- From:
International Journal of Cerebrovascular Diseases
2017;25(3):281-284
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral venous and sinus Thrombosis (CVST) is a rare ischemic cerebrovascular disease,the lesions of 60% patients are involved in multiple venous sinus,of which the superior sagittal sinus thrombosis is most common.The pathogenesis and pathophysiology of CVST has not yet been fully elucidated,and the establishment of stable and ideal animal models can provide a basis for the study of its development,prognosis and efficacy assessment.This article summarizes the characteristics and advantages of several available CVST models,but each method has its own limitations.Therefore,the establishment of a more ideal animal model will help to fully understand the pathogenesis and pathological process of CVST.
