Experimental study on lung-damaging agents:research advances

VernacularTitle:肺损伤性毒剂的实验研究进展
Author: Zike LI ; Jian ZHAO ; Rigao DING
Keywords: lung-damaging agent; phosgene; acute lung injury; pathogenic mechanisms; biomarker
From: Journal of International Pharmaceutical Research 2017;44(6):527-530,543
CountryChina
Language:Chinese
Abstract: Lung is the main target of lung-damaging agents(or choking agents,lung irritants)which can result in potential permanent respiratory depression,the rapid development of acute lung injury(ALI)and pulmonary edema,even death in severe cas-es. Recently,with the research progress in the pathogenesis of lung-damaging agents,numerous corresponding experimental studies were carried out and some progress were made. This paper summarizes the progress in the study of lung-damaging agents on the re-search situation,pathogenic mechanism and biomarker,to provide reference for the promotion of ALI prevention,medical antagonis-tic measures and clinical treatment.