A comparison of 20-MHz and 50-MHz ultrasonography in imaging and measuring the skin
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0412-4030.2017.07.004
   		
        
        	
        		- VernacularTitle:20MHz与50MHz超声皮肤成像与测量的比较研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Menglong RAN
			        		
			        		;
		        		
		        		
		        		
			        		Dehua LIU
			        		
			        		;
		        		
		        		
		        		
			        		Jingqiu ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Ping TU
			        		
			        		;
		        		
		        		
		        		
			        		Shuxia YANG
			        		
			        		;
		        		
		        		
		        		
			        		Hang LI
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasonography;
			        		
			        		
			        		
				        		Skin structure;
			        		
			        		
			        		
				        		Skin thickness;
			        		
			        		
			        		
				        		Interclass correlation coefficient
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Dermatology
	            		
	            		 2017;50(7):482-486
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate imaging characteristics of human skin in different sites by using 20-MHz and 50-MHz high-frequency ultrasonography,and to compare the reliability of skin thickness measurement by the above two approaches of ultrasonography.Methods A total of 39 healthy volunteers aged 18-39 years were enrolled into this study.Then,20-MHz and 50-MHz ultrasonography were separately performed to image 20 different sites on the body,and the thickness of the epidermis and dermis were measured and evaluated by 3 dermatologists independently.The ultrasonic images were analyzed,and the intraclass correlation coefficient (ICC) was used to assess and compare the reliability of skin thickness measurement by 20-MHz and 50-MHz ultrasound.Results The ICC values were less than or close to 0.7 in epidermal thickness measurement at almost all the tested sites between 20-MHz and 50-MHz ultrasonography,suggesting poor reliability.However,20-MHz and 50-MHz ultrasonography showed excellent reliability in dermal thickness measurement with the ICC greater than 0.75 at almost all the tested smooth and flat body sites.The 20-MHz ultrasound could provide clear images of the dermis and subcutaneous tissue,while 50-MHz ultrasound could only provide clearer images of the dermis in details.In some uneven sites with complex anatomical structures,20-MHz and 50-MHz ultrasound probes had their own advantages and disadvantages in imaging depth and detail resolution.Conclusions The 20-MHz and 50-MHz ultrasono-graphy both can serve as non-invasive imaging techniques to show structures of the epidermis and dermis better.In different parts of human body,ultrasound frequencies should be selected according to their imaging characteristics.